Some of the later generations of Pokémon (well, later by the standards of someone who started playing in the 90s) introduced a bunch of little freaks who are more or less just mundane, inanimate objects with faces. These are some of my favorite Pokémon because it feels like whoever designed them was just glancing around the room, looking for anything they could anthropomorphize.
Advances in organ and computer models are raising the prospect that some animal experiments could be eliminated. But there are still huge hurdles to overcome.
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The backend for the game - Snake Session Handler Daemon or sshd - is capable of handling thousands of concurrent players and rendering over a hundred million pixels a second.